Which antidepressant causes most weight gain?

July 2024 ยท 6 minute read
Tricyclic antidepressants such as amitriptyline and tetracyclic antidepressants such as mirtazapine are linked to the most weight gain.

Which antidepressants do not cause weight gain?

Some antidepressants may be less likely to affect weight. Effexor and Serzone generally do not cause weight gain, while Wellbutrin can cause weight loss.

Which causes more weight gain Prozac or Zoloft?

That being said, one study published in 2016 in the Journal of Clinical Medicine found that Zoloft can lead to an overall greater weight gain than Prozac when taken long-term. The study found that people taking Prozac for two years gained an average of 4.6 pounds.

Why do most antidepressants cause weight gain?

Antidepressants interfere with serotonin, the neurotransmitter that regulates anxiety and mood while also controlling appetite. In particular, these changes may increase cravings for carbohydrate-rich foods, such as bread, pasta, and desserts.

What are the best antidepressants for weight loss?

Most antidepressant medications are more commonly associated with weight gain, but there are three that have been connected to weight loss:

How psychiatric drugs can cause weight gain

Can Wellbutrin help weight loss?

Long-term Wellbutrin treatment may support modest weight loss in normal weight or overweight people who have been diagnosed with depression, with the percent of weight loss increasing based on body size.

How fast is weight loss on Wellbutrin?

Bupropion seems to be effective for weight-loss maintenance as well. A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012).

Is antidepressant weight gain permanent?

The research also raises concerns about the duration of risk that patients are exposed to. Previous studies correlating antidepressants with weight gain have been short-term, typically less than a year.

Does everyone gain weight on Lexapro?

Lexapro is the brand name for a drug called escitalopram, which is a treatment for anxiety and depression. Taking Lexapro may cause a person to gain a small amount of weight. Less commonly, it can cause weight loss. A healthful diet and regular exercise can help to prevent unwanted changes in weight.

Can Zoloft help weight loss?

Weight gain is a common complaint of patients receiving antidepressant drug treatment. The antidepressant sertraline, a selective serotonin uptake inhibitor, has been reported to promote weight loss.

Is Prozac better than Wellbutrin?

Is Wellbutrin or Prozac better? Wellbutrin and Prozac are similarly effective for treating depression. The best antidepressant is the one that causes the least side effects and is more cost effective, depending on the situation. Wellbutrin causes less sexual side effects and weight gain than SSRIs like Prozac.

Does everyone gain weight on Zoloft?

Official answer. Zoloft (sertraline) may lead to a small weight gain ranging from 1% to 1.6% of initial body weight when used over 6 months to 1 year. For example, in a 150 lb (68 kg) person, this would equal an added 1.5 to 2.4 lbs (0.7 to 1.1 kg) of weight.

Which is better Zoloft or Lexapro?

A 2014 study published in International Clinical Psychopharmacology suggested that Lexapro may be more effective and better tolerated than Zoloft or Paxil. Lexapro has different binding site interactions which may lead to better efficacy and tolerability.

Is Wellbutrin a good antidepressant?

Wellbutrin has been found to be at least as effective as other popularly prescribed antidepressant medication. There is also less chance of weight gain, sleepiness, and sexual dysfunction than with other forms of treatment. It may even work actively against sexual dysfunction resulting from previous antidepressant use.

Does Lexapro help you lose weight?

There are some reports that people begin to lose weight when first taking Lexapro, but this finding is not well supported by research studies. Another study found that Lexapro didn't reduce the obsessive-compulsive symptoms linked to binge-eating disorder, but it did reduce weight and body mass index.

Is Effexor better than Wellbutrin?

Effexor and Wellbutrin are both effective drugs that treat depression. Effexor is better than Wellbutrin for treating anxiety disorders that are experienced alongside depression. However, compared to Wellbutrin, Effexor may cause more sexual side effects, such as abnormal ejaculation and impotence.

Which is better effexor or Lexapro?

The results found that both Effexor and Lexapro were similarly effective at treating depression, and both were more effective than many other antidepressant medications. However, Effexor's side effect profile may make it more difficult to tolerate than Lexapro.

Is Prozac better than Lexapro?

When considering Prozac vs Lexapro, both medications are approved to treat major depressive disorder (MDD). A 2014 study found that Lexapro was more effective than Prozac in treating severe periods of depression.

How much weight did you gain on Lexapro?

Study participants taking escitalopram gained, on average, less than a third of a pound in 12 weeks. Those taking nortriptyline gained almost 10 times as much weight. Additionally, some people may be more likely than others to gain weight while taking Lexapro.

Will I lose the weight I gained from antidepressants?

Although some SSRIs are associated with weight loss at first, long-term use of SSRIs is mostly linked to weight gain. Long-term use is considered treatment that lasts longer than six months. Of the SSRIs listed above, paroxetine is most commonly associated with weight gain with both long-term and short-term use.

How does Wellbutrin cause weight loss?

It stimulates noradrenaline, dopamine, and (less-so) serotonin receptors. This gives you more energy, suppresses your appetite, and enhances your mood. Stress increases cortisol and ghrelin which stimulate your appetite. Dopamine and noradrenaline suppress your appetite.

Does Wellbutrin cause weight gain?

Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more. In the same studies, 11% of people gained more than 5 pounds.

What is the difference between Lexapro and Wellbutrin?

While both Wellbutrin and Lexapro treat depression, they are not the same type of drug, Wellbutrin works by blocking the reuptake of dopamine and norepinephrine in the neuronal synapse, while Lexapro blocks the reuptake of serotonin. All of these neurotransmitters play a role in mood and affect.

Does Wellbutrin give you energy like Adderall?

With the increase of dopamine that Wellbutrin provides, some patients may experience a boost of energy and motivation while taking Wellbutrin.

Is Wellbutrin the same as Contrave?

CONTRAVE contains bupropion, the same active ingredient as some other antidepressant medications (including, but not limited to, WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, and APLENZIN). Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials.

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